A traveller’s medical kit laid out with prescription packaging and rehydration sachets
Heritage Persia · Plan Your Trip

Iran Health & Vaccinations

The vaccine list, the honest risk order, and the medicine shortage that changed the advice in 2026.

Read Time
12 min
Reviewed
12 Sep 2026
Required
None
Recommended
Hep A
Author
Heritage Persia

Most health advice for Iran leads with vaccinations, which is roughly the least important thing on this page. The realistic risk order for a visitor is road traffic first, air quality second, heat third, and infectious disease a long way down — and the one item that has genuinely changed in 2026 is not a disease at all but the supply of medicine.

What follows is the vaccine list from the source that sets it, then the part we would actually spend your attention on: what you can no longer assume you will be able to buy once you are there.

⚡ Quick Answer 30 seconds · full guide below
No vaccine is required to enter Iran from Europe or North America
Hepatitis A is recommended for everyone; the rest depend on what you do
Bring every medicine you might need. Iran is short of about 800 of them
Tap water is safe in every city on the standard route
Road traffic is the real risk, by a wide margin
Winter air in the big cities is a genuine health issue

Two things before you read on. This page is a traveller’s summary and not medical advice — see a travel clinic or your own doctor six to eight weeks before departure, because some courses need that long. And whether to travel to Iran at present is a separate question with a different answer: as of 10 September 2026 ours is no, and the situation report explains why.

The Vaccine List

Iran requires no vaccination certificate for entry from Europe or North America. A yellow fever certificate is required only if you are arriving from a country with a risk of transmission, which is the sole entry condition of this kind. Everything below is a recommendation rather than a rule, and the grouping follows the UK National Travel Health Network and Centre.

VaccineWhoWhy hereLead time
Routine UK/EU schedule
MMR, diphtheria-tetanus-polio
EveryoneBeing up to date matters more than any travel-specific vaccine on this listCheck now; a booster may need weeks
Hepatitis AEveryone not already vaccinatedThe one travel vaccine recommended for all visitors to Iran. Food and water transmission2 weeks before departure
TetanusAnyone whose last dose was over ten years agoRelevant to any cut or animal bite, which is the scenario that actually occurs2 weeks
TyphoidSome — poorer sanitation, staying with families, long tripsWorth it if you are eating widely outside hotels and restaurants2 weeks
Hepatitis BSome — long stays, medical procedures, certain exposuresWorth discussing if a hospital visit is plausible, which it is more than usual here3–8 weeks for the full course
RabiesSome — remote areas, stays over a month, cycling or trekkingRabies is present in domestic animals. Pre-exposure cover buys time rather than immunity3–4 weeks for the course
CholeraRarely — outbreak or humanitarian workNot a normal tourist recommendation1–2 weeks
Yellow feverOnly if arriving from a risk countryThe one genuine entry requirement, and it does not apply from Europe or North America10 days before arrival

Malaria is not a consideration on the classic route. Low risk exists from March to November in rural south-eastern provinces and parts of the northern border; the corridor from Tehran to Shiraz has none, and no antimalarials are normally advised for a standard itinerary.

Chart of eight vaccines for travel to Iran showing who needs each and how much lead time it requires
Eight vaccines, and who actually needs each. Only two apply to every traveller, and none is required to enter the country.

The Part That Changed in 2026

For years the honest advice was that Iranian pharmacies were cheap, everywhere, and better stocked than visitors expected, with most medicines sold without the prescription they would need at home. That is no longer a safe assumption, and we have corrected it elsewhere on this blog rather than leave it standing.

As of September 2026 Iran is short of roughly eight hundred pharmaceutical products, ninety of them classed as essential or life-saving, according to Hadi Ahmadi of the Iranian Pharmacists Association. Four hundred of the scarce items are ones Iran manufactures itself. The categories affected include cancer drugs, epilepsy and nerve-pain medication, antibiotics, insulin, antidepressants, and rotavirus and influenza vaccines.

Prices have moved with the shortage. Year on year, gabapentin is reported up 220 per cent, paracetamol 375 per cent, amoxicillin 285 per cent, fluoxetine 100 per cent and insulin by as much as 600 per cent.

The causes are stacked rather than singular: around forty-four pharmaceutical and medical-equipment companies damaged or destroyed since February 2026, a naval blockade restricting shipping through the Strait of Hormuz along with air, rail and overland routes, continued dependence on imported active ingredients, and the withdrawal of subsidised foreign currency for medical imports.

What this means for you, in one sentence. Bring every medicine you might plausibly need, including the ordinary ones — paracetamol, an antihistamine, rehydration salts, a course of antibiotics if your doctor will prescribe one — because the assumption that you can buy them on arrival no longer holds reliably. The packing list has the full kit.

Bringing Your Own Medicines

Bring more than the trip requires — a week's surplus is the usual rule and we would double it here — and split it between your hand luggage and your case so that a delayed bag is an inconvenience rather than an emergency.

Keep everything in original packaging with the pharmacy label, and carry a copy of the prescription, ideally in English and naming the generic drug rather than only the brand. Brand names differ between countries and a generic name is what an Iranian pharmacist or doctor will recognise.

Some categories need more care. Medicines containing codeine, strong painkillers, sedatives and stimulants are controlled and may require documentation at the border; bring the prescription and only the quantity the trip needs. Any medicine that is contentious at home is likely to be contentious here, and the sensible step is to check your specific drug with the Iranian consulate before you fly rather than discover the answer at the airport.

If you use insulin or anything else that needs refrigeration, plan for it explicitly. Courtyard hotels do not always have room fridges, summer road transfers are long and hot, and insulin is among the medicines currently in shortest supply locally, so a cool bag and your own stock are not optional.

The Honest Risk Order

This is the table we would actually hand a traveller. It is ordered by how likely each item is to affect your trip, not by how alarming it sounds.

RiskHow realWhere and whenWhat actually reduces it
Road trafficThe largest by a wide marginEverywhere, worst on intercity roads and at nightSeat belts in every seat, a driver who works the route, and refusing night drives. See getting around
Air qualityA genuine public health problemTehran and nine other cities, worst November to FebruaryPlan winter city days around the morning, carry an inhaler if you use one, and check the daily index
HeatSerious in the wrong monthYazd, Kerman, Khuzestan and the Gulf, May to SeptemberTravel in the shoulder seasons, and treat Khuzestan as closed in summer
Stomach upsetsCommon and mildAnywhere, usually from unfamiliar food rather than unsafe foodRehydration salts in the bag. Tap water in the cities is not the cause
SunUnderrated at altitudeThe whole plateau sits at 1,200–1,800 m; Persepolis has no shade at allA wide hat and high-factor sunscreen, brought with you
Animal bitesUncommon but consequentialStreet dogs and cats, rural areasNo contact with animals; wash any bite immediately and seek care the same day
AltitudeNot an issue on the standard routeOnly above 2,500 m — Damavand, Alborz trekking, DizinGradual ascent if you are going up. The cities are all comfortably below the threshold
MalariaNot a consideration on the classic routeLow risk March–November in rural south-east and parts of the northBite avoidance if you go there. No prophylaxis for a normal itinerary

Notice that the two largest items are environmental rather than infectious, and that both are addressed by when and how you travel rather than by anything a clinic can give you.

Winter Air in the Cities

Iran's air pollution is not a footnote. Government-linked figures attribute nearly fifty-nine thousand deaths in the Iranian year to March 2025 to air pollution — around a hundred and sixty a day — with economic damage put at $17.2 billion. Ten major cities, including Tehran, Isfahan, Mashhad, Tabriz, Ahvaz and Yazd, exceeded WHO limits for fine particulates on hundreds of days, some districts at four to nine times the safe threshold.

For a visitor this matters mainly in winter and mainly in Tehran, where cold air sits trapped under the Alborz and the index climbs through November, December and January. Schools and offices close in the worst episodes, which is the signal to change your own plans rather than push through.

The practical response is modest: if you are travelling between November and February, weight your city days towards the morning, keep a reliever inhaler with you if you have asthma, and treat a heavily polluted day as a reason to take an indoor museum rather than a walking route. Isfahan and Shiraz are consistently better than Tehran, and Yazd and the desert are better again.

Food and Water

Tap water is treated and safe to drink in every city on the standard route, and Iranians drink it. In villages and in the far south we would use bottled or filtered water, which is what local practice does too.

Food-borne illness is uncommon and usually mild. Salads and herbs are washed as a matter of course in restaurants and the fresh herb plate served with almost every meal is not a risk worth avoiding. Street food is generally safe; the usual rule of eating where there is turnover applies here as anywhere.

Two genuine cautions. Unpasteurised dairy in rural areas carries a brucellosis risk and is worth declining. And raw camel products are best avoided on account of MERS, which has been reported in the region — this affects almost no ordinary itinerary but is the reason the advice exists. The food guide covers what to eat rather than what to avoid, which is the more useful half.

What Care Is Actually Like

Uneven, and better than most travellers expect where it is good. Global Affairs Canada puts it accurately: good health care is limited in availability and quality varies greatly across the country. Tehran, Isfahan, Shiraz and Mashhad have private hospitals with foreign-trained specialists and equipment that would not look out of place in southern Europe; provincial towns are a different proposition and rural areas more so again.

Two things about paying. More than seventy per cent of healthcare costs in Iran are met directly by patients rather than by insurance, so the cash-at-the-counter model you will encounter is the normal domestic one rather than something applied to foreigners. And because sanctions make it difficult for a Western insurer to transfer funds to an Iranian hospital, you pay in cash and claim afterwards — which our insurance guide sets out in full, including why your cash reserve is the real cover below the evacuation threshold.

Plan the route with the medical map in mind if you have a condition that could need attention. The classic corridor keeps you within about an hour of a major hospital throughout; the Lut, the Khuzestan plain and the mountain routes do not.

What We Would Actually Do

See a travel clinic six to eight weeks out. Hepatitis A and a tetanus check are the whole conversation for most people, and both are quick.

Build the medical kit first, not last. In 2026 it is the single most consequential thing in the suitcase, and the packing list has the contents.

Carry a one-page medical summary with your conditions, allergies, generic drug names and doses, and an emergency contact — in English, on paper, in your bag rather than only in your phone.

Choose the month with health in mind, because the two biggest risks on this page are seasonal. The month-by-month guide is the place to start.

And read the insurance page before you book, not after. When your government advises against all travel, the ordinary policy that would have paid for a medical evacuation does not.

✉️ Travelling with a condition that needs planning? Tell us what it is and we will tell you where on the route the hospitals are, which legs we would change, and what to bring rather than expect to buy. Talk to our team →

Bar chart ranking the health risks of travel in Iran, with road traffic highest and malaria lowest
The risk order as we would rank it. The two largest items are environmental, and both are answered by when you travel rather than by a clinic.

Continue reading

Frequently Asked Questions

What travellers ask our guides, answered on the ground.

None are required to enter from Europe or North America. Hepatitis A is recommended for all previously unvaccinated travellers, a tetanus booster if your last dose was over ten years ago, and your routine schedule should be up to date. Typhoid, hepatitis B and rabies are recommended for some travellers depending on where you go and how long you stay. A yellow fever certificate is required only if you arrive from a country with a risk of transmission.
Not reliably, and this changed in 2026. Iran is short of roughly eight hundred pharmaceutical products, ninety of them classed as essential or life-saving, according to the Iranian Pharmacists Association — including antibiotics, insulin, antidepressants and epilepsy medication. Prices for what remains have risen sharply year on year. Bring every medicine you might plausibly need, including ordinary ones like paracetamol.
Yes, in every city on the standard route. The water is treated and Iranians drink it. In villages and in the far south we would use bottled or filtered water, which is what local practice does too. Bringing a refillable bottle and filling it at the hotel is the sensible approach, and food-borne illness is uncommon and usually mild.
Not for the classic route. Low risk exists from March to November in rural south-eastern provinces and parts of the northern border, and very low risk elsewhere; the corridor from Tehran through Isfahan and Yazd to Shiraz has none. Antimalarials are not normally advised for a standard itinerary, and bite avoidance is the recommendation if you travel to the risk areas.
Road traffic, by a wide margin, and it is not close. Air quality is second — Iran attributes nearly fifty-nine thousand deaths a year to air pollution, and ten major cities exceed WHO limits for fine particulates on hundreds of days. Heat is third, in the wrong month. Infectious disease sits a long way down the list, which is the opposite of how most health advice for Iran is ordered.
Bad enough to close schools. Government-linked figures attribute nearly fifty-nine thousand deaths in the year to March 2025 to air pollution, around a hundred and sixty a day, with economic damage put at $17.2 billion. Ten major cities exceeded WHO fine-particulate limits on hundreds of days. For visitors it matters mainly between November and February and mainly in Tehran, where cold air sits trapped under the Alborz.
Yes, with sensible precautions. Keep everything in original packaging with the pharmacy label, carry a copy of the prescription in English naming the generic drug rather than only the brand, and bring only the quantity the trip needs plus a surplus. Medicines containing codeine, strong painkillers, sedatives and stimulants are controlled and may require documentation — check anything contentious with the Iranian consulate before you fly.
Uneven, and better than most travellers expect where it is good. Tehran, Isfahan, Shiraz and Mashhad have private hospitals with foreign-trained specialists; provincial towns are a different proposition and rural areas more so. More than seventy per cent of healthcare costs in Iran are paid directly by patients, so the cash-at-the-counter model you encounter is the normal domestic one rather than something applied to foreigners.
Generally yes, and food-borne illness is uncommon and usually mild. Salads and the fresh herb plate served with almost every meal are washed as a matter of course and are not a risk worth avoiding. The usual rule of eating where there is turnover applies. The two genuine cautions are unpasteurised dairy in rural areas, which carries a brucellosis risk, and raw camel products.
Not on the standard route. Altitude sickness is a risk above 2,500 metres and the cities all sit comfortably below it — Tehran around 1,200 metres, Isfahan 1,570, Kerman 1,750. It becomes relevant only for Damavand, Alborz trekking or the ski resorts. What the altitude does affect everywhere is the sun, which is stronger on the plateau than most visitors expect.

The Heritage Persia Guiding Team

Licensed Iranian Tour Operator · Shiraz

The risk order on this page is ordered by what actually affects trips rather than by what sounds alarming, which is why road traffic sits above infectious disease. The 2026 medicine shortage made us go back and correct three other pages on this blog that said pharmacies here were well stocked.

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